- Best practices for covariate model development. Kinjal Sanghavi is leading the preparation of a position paper (or maybe two!) on the topic. A first draft is being readied in 2019.
- A first summary of the Data Standards Survey has been released!
- The first MoEv tutorial has been published!
- Our commentary on drug-drug interactions has been published!
The Standards & Best Practices Committee provides best practices and recommendations for standard pharmacometric analyses (e.g. population PK/PD, exposure-response, disease models) with the goal to increase consistency, productivity, quality, communication, and impact of pharmacometrics on decision making. In the future, we anticipate expanding to cover QSP as well.
The Committee’s activities are concentrated into two main workstreams.
Model Evaluation Working Group (“MoEv”)
The Model Evaluation Working Group (“MoEv”) is tasked with producing a series of model evaluation tutorials for publication in the peer-reviewed literature. So far, three have been planned; of these, one is accepted, one is undergoing internal review, and one is in active development. The MoEv group is led by France Mentré.
Data Standards Working Group
The Data Standards Working Group is developing a set of standards for population PK datasets, which we ultimately hope will be folded into the CDISC standard, and investigating ways to improve the provenance of source data. The Data Standards group is led by Andrijana Radivojevic.
Do you have any ideas for our Committee? Want to join one of the above activities? Contact us!
The current chair of the Standards and Best Practices Committee is Jonathan French.