The Lewis B. Sheiner Lecturer Award was established in 2008 to honor the memory of Dr. Lewis B. Sheiner (1940-2004). The Award is intended to acknowledge Dr. Sheiner’s exceptional and outstanding lifetime career achievements and leadership in the field of pharmacometrics. This award constitutes the highest recognition by ISoP.
Dr. Lewis B. Sheiner, MD, PhD (honoris causa), also known as the father of the “learn and conﬁrm” paradigm of drug development, is internationally recognized for his work in pharmacokinetic (PK) and pharmacodynamic (PD) modeling and simulation. He pioneered the scientific discipline of pharmacometrics with an academic career focused on developing and applying mathematical and statistical methods to problems in clinical pharmacology. In a close and extended collaboration with Dr. Stuart Beal, they developed the methodology for the population approach to PK/PD, based on the estimation of non-linear mixed effects modeling (NONMEM), and further developed the NONMEM software system. The latter quickly became the standard software in many pharmaceutical industries and at the U. S. Food and Drug Administration (FDA) for characterizing PK and PD data acquired during clinical drug studies.
Dr. Sheiner authored more than 200 articles and book chapters. He served on the Editorial Board of Clinical Pharmacology & Therapeutics and was an editor of the Journal of Pharmacokinetics and Pharmacodynamics. He was a former member of the Antiviral Drugs Advisory Committee of the FDA and a member of the Clinical Pharmacology Subcommittee of the Advisory Committee for Pharmacological Science of the FDA. His honors and awards include an honorary doctorate degree from Uppsala University in Sweden, the Rawls Palmer Progress in Medicine Award from the ASCPT, and numerous named lectureships at universities throughout the world.
Purpose of the Award
The purpose of the Lewis B Sheiner Lecturer Award is to recognize the outstanding lifetime achievements of a distinguished scientist or researcher who has continued the legacy of excellence in pharmacometric research and leadership established by Lewis B. Sheiner. In particular, pharmacometric scientists or researchers involved in the application of the circle of excellence: Integration–Innovation–Impact (JCP 2010;50:S6-S160) to enhance research, development, regulatory evaluation, and/or utilization of therapeutic products may be considered for this award.
The candidate must:
- be a leader and actively advance and impact the scientific discipline of pharmacometrics
- have a continued track record of quality scientific publications in pharmacometrics
- The following individuals are ineligible for ISoP Award nomination during AND until one year after completion of serving their term or stepping down from their position: ISoP Board members (Executive Committee members included), Leadership (Chair, Vice Chair and/or Chair Elect) of the following ISoP committees – Awards Committee, Conference Committee, Finance Committee and Nominations Committee.
- Individuals who have won an ISoP Award within preceding 2 years are ineligible for nomination of this ISoP Award.
- be capable of delivering an engaging and comprehensive lecture on pharmacometrics
- attend the ACoP Annual Meeting to receive the Award and deliver the lecture
Nomination Procedure and Package
- Nominations can be made by any ISoP member.
- The call for nominations to this Award is open through the published deadline.
- The nomination package should contain:
- Nomination letter. The letter must clearly document why the candidate should be considered, above all others, for this distinguished award.
- Curriculum Vitae (CV) of the nominee. The CV must contain sufficient information to inform the selection process without additional research.
- List of select publications from the candidate (as first and/or senior author) that illustrate the nominee’s candidacy particularly well.
- The nomination package must be sent by the call deadline to: firstname.lastname@example.org
The Award recipient will be selected based upon the following steps:
- Individual scoring of the nominated candidates by the ISoP Awards Committee members
- Ranking of the nominated candidates based on highest total score and recommendation of the recipient by the ISoP Awards Committee
- Approval of the Award recipient by the ISoP Board
Notification of Award:
- The recipient of the award will be notified via email promptly after selection.
- The recipient will be requested to RSVP within 15 days as to accept/decline the Award.
- The name of the Award recipient will be publicly announced to the ISoP community after acceptance of the Award by the recipient.
Recognition of Award Recipient
The recipient of the Lewis B. Sheiner Lecturer Award will be recognized at the opening ceremony of the ACoP Annual Meeting. The Award recipient will present a lecture (1 hour) summarizing the work that forms the basis of the award. In addition, the recipient will receive a plaque. Travel expenses, hotel expenses (up to $1,000), and the ACoP Annual Meeting registration fee will be reimbursed by ISoP.