ACoP10 Pre-conference: Clinical Pharmacometrics: Bringing Models to Patients
The annual ACoP Preconference aims to provide an in-depth coverage on a specific theme or topic(s) of impact and interest to our community. This year’s Preconference theme is “Clinical Pharmacometrics: Bringing Models to Patients”, which will focus on the application of pharmacometrics to direct patient care. The planned program is intended to bring together pharmacometricians with clinical interests and clinicians with an interest in pharmacometrics. Given the scope, this year’s Preconference is has been developed in close collaboration with the Clinical Pharmacometrics Special Interest Group.
The day will start with a keynote address introducing the audience to bedside pharmacometric tools, an overviewing of the development and regulatory approval of a bedside pharmacometric tool used to treat patients with hemophilia, and highlighting the challenges to widespread use of the tool in clinical practice. Following this introduction, there will be two talks on recent advancements in the field, both in clinical practice and in drug development. The final morning session will consist of four speakers of varying backgrounds, each highlighting a challenge in this space followed by a potential solution. Topics will include pharmacokinetic model validation, special populations, electronic-medical record integration, and software development standards.
The afternoon will feature a poster session, a hands-on session showcasing bedside pharmacometric tools across various therapeutic areas, and a regulatory session highlighting the various requirements for approval of bedside pharmacometric tools. The pre-conference will wrap up with a panel discussion on moving this field forward. Following the event, the proceedings from the pre-conference will be summarized and a plan to continue discussions will be formed.